Langman's Medical Embryology With the Point Access Scratch Code (With CD – ROM) Widely acclaimed for its clinical relevance and clear writing style, Langman's Medical Embryology provides a user-friendly and innovative approach to learning embryology. The revised eleventh edition presents medical and health professions students with a concise yet thorough description of embryology and its clinical significance, an awareness of which is essential in the diagnosis, and prevention of birth defects. It features outstanding full-color clinical images and photographs, end-of-chapter Summaries, Problems to Solve, and Clinical Correlates boxes. A companion Website includes fully searchable text, interactive review questions and problems, updated Simbryo animations of embryologic system development, and PowerPoint slides for instructors. Salienteatures NEW! Additional images included in the birth defects chapters to provide more visual examples and improve the usability of the chapter NEW! Additional recolorization/replacement of line drawings (approximately 15-20) NEW! Continued replacement/addition of color clinical photographs/images NEW! Glossary of key terms NEW! Updated and new Problems to Solve NEW! Updated information on molecular genetics Clinical Correlates provide information about birth defects and other clinical entities directly related to embryologic concepts Full-color art program along with supporting color clinical images and photographs General chapter on development includes coverage of molecular biology Organized into two parts: Part One, General Embryology, presents development of embryo chronologically and also includes chapters on placental and fetal development and prenatal diagnosis and birth defects Part Two, Systems-based Embryology, describes the embryogenesis of each organ system Provides end-of-chapter Summaries and Problems to Solve ANCILLARYASSETS Online student resources: Fully search able text Interactive review questions and problems Simbryo animations of embryologic organ and system development: this edition includes updated and additional animations Online faculty resourcesespecially helpful for Nursing and other markets outside Medicine: Pre-built PowerPoint slides Image Bank AboutTheAuthor Thomas W Sadler PhD, Adjunct Professor of Pediatrics, School of Medicine, University of Utah, Salt Lake City, UT; Visiting Professor of Embryology,Quillen School of Medicine, East Tennessee State University, Johnso Table of Contents Part One General Embryology • Chapter 1 Embryology: Old and New Frontiers and an Introduction to Molecular Regulation and Signaling/ Clinical Relevance/A Brief History of Embryology/Introduction to Molecular Regulation and Signaling • Chapter 2 Gametogenesis: Conversion of Germ Cells into Male and Female Gametes/Primordial Germ Cells/ Clinical Correlates/The Chromosome Theory of Inheritance/Clinical Correlates/Morphological Changes during Maturation of the Gametes/Clinical Correlates • Chapter 3 First Week of Development: Ovulation to Implantation/Ovarian Cycle/Clinical Correlates/Fertilization/Clinical Correlates/Cleavage/Blastocyst Formation/Clinical Correlates/Uterus at Time of Implantation • Chapter 4 Second Week of Development: Bilaminar Germ Disc/Day 8/ Day 9/Days 11 and 12/Day 13/Clinical Correlates • Chapter 5 Third Week of Development: Trilaminar Germ Disc/Gastrulation: Formation of Embryonic Mesoderm and Endoderm/Formation of the Notochord/Establishment of the Body Axes/Fate Map Established during Gastrulation/Growth of the Embryonic Disc/Clinical Correlates/Further Development of the Trophoblast • Chapter 6 Third to Eighth Weeks: The Embryonic Period/Derivatives of the Ectodermal Germ Layer/Derivatives of the Mesodermal Germ Layer/Clinical Correlates/Derivatives of the Endodermal Germ Layer/Patterning of the Anteroposterior Axis: Regulation by Homeobox Genes/External Appearance during the Second Month/Clinical Correlates • Chapter 7 Third Month to Birth: The Fetus and Placenta/Development of the Fetus/Clinical Correlates/Fetal Membranes and Placenta/Clinical Correlates/Structure of the Placenta/Clinical Correlates/Clinical Correlates/Amnion and Umbilical Cord/ Clinical Correlates/Placental Changes at the End of Pregnancy/Amniotic Fluid, Clinical Correlates/Fetal Membranes in Twins/Clinical Correlates/Parturition (Birth)/Clinical Correlates • Chapter 8 Birth Defects and Prenatal Diagnosis/Birth Defects/ Clinical Correlates/Prenatal Diagnosis/Fetal Therapy Part Two Systems-based Embryology • Chapter 9 Skeletal System/Skull/ Viscerocranium/Clinical Correlates/Limbs/Clinical Correlates/Vertebrae and the Vertebral Column/Clinical Correlates/Ribs and • Sternum • Chapter 10 Muscular System/Striated Skeletal Musculature/Molecular Regulation of Muscle Development/Patterning of Muscles/Derivatives of Precursor Muscle Cells/Head Musculature/Limb Musculature/ Clinical Correlates/Cardiac Muscle/ Smooth Muscle • Chapter 11 Body Cavities/Formation of the Intraembryonic Cavity/Clinical Correlates/Serous Membranes/Diaphragm and Thoracic Cavity/Formation of the Diaphragm • Clinical Correlates • Chapter 12 Cardiovascular System/ Establishment of the Cardiogenic Field/ Formation and Position of the Heart Tube/Formation of the Cardiac Loop/Clinical Correlates/Molecular Regulation of Cardiac Development/Development of the Sinus Venosus/Formation of the Cardiac Septa/ Clinical Correlates/Clinical Correlates/ Clinical Correlates/Formation of the Conducting System of the Heart/Vascular Development/Clinical Correlates/Clinical Correlates/Circulation before and after Birth • Chapter 13 Respiratory System/ Formation of the Lung Buds/Clinical Correlates/Larynx/Trachea, Bronchi, and Lungs/Maturation of the Lungs/Clinical Correlates • Chapter 14 Digestive System/Divisions of the Gut Tube/ Molecular Regulation of Gut Tube Development/MesenterieForegut/ Clinical Correlates/Clinical Correlates/ Clinical Correlates/Molecular Regulation of Liver Induction/Pancreas/ Clinical Correlates/Midgut/Clinical Correlates/Hindgut/Clinical Correlates • Chapter 15 Urogenital System/Urinary System/Clinical Correlates/Clinical Correlates/Clinical Correlates/Genital System/Clinical Correlates/Clinical Correlates/Clinical Correlates/Clinical Correlates • Abbreviated