Aulton's Pharmaceutics : The Design and Manufacture of Medicines (Paperback)

Pharmaceutics is one of the most diverse subject areas in all of pharmaceutical science. In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms for medicines. An understanding of pharmaceutics is therefore vital to all pharmacists and pharmaceutical scientists who are involved in converting a drug or a potential drug into a medicine that can be delivered safely, efficiently and conveniently to the patient.

Professor Aulton's Pharmaceutics has become established as the clearest, most comprehensive textbook on this subject. The book provides pharmacy and pharmaceutical science students with the latest information on all aspects of pharmaceutics.

Table of Contents
* What is pharmaceutics?
* Design of dosage forms

PART ONE: SCIENTIFIC PRINCIPLES OF DOSAGE FORM DESIGN
* Dissolution and solubility
* Properties of solutions
* Rheology
* Surface and interfacial phenomena
* Disperse systems
* Kinetics of product stability

PART TWO: PARTICLE SCIENCE AND POWDER TECHNOLOGY
* Solid-state properties
* Particle size analysis
* Particle size reduction
* Particle size separation
* Mixing
* Powder flow.

PART THREE: PHARMACEUTICAL MICROBIOLOGY AND STERILIZATION
* Fundamentals of microbiology
* Pharmaceutical applications of microbiological techniques
* Action of physical and chemical agents on microorganisms
* Principles of sterilization
* Sterilization in practice

PART FOUR: BIOPHARMACEUTICAL PRINCIPLES OF DRUG DELIVERY

Introduction to biopharmaceutics
* The gastrointestinal tract ? physiology and drug absorption
* Bioavailability ? physicochemical and dosage form factors
* Assessment of biopharmaceutical properties
* Dosage regimens

PART FIVE: DOSAGE FORM DESIGN AND MANUFACTURE
* Pharmaceutical preformulation
* Solutions
* Clarification
* Suspensions and emulsions
* Powders and granules
* Granulation
* Drying
* Tablets and compaction
* Modified-release peroral dosage forms
* Coating of tablets and multiparticulates
* Hard gelatin capsules
* Soft gelatin capsules
* Pulmonary drug delivery
* Nasal drug delivery
* Transdermal drug delivery
* Wound dressings
* Rectal and vaginal drug delivery
* Delivery of pharmaceutical proteins
* Packs and packaging
* Microbiological contamination, spoilage and preservation of medicines
* Product stability and stability testing
* Pharmaceutical plant design
* Heat transfer and the properties and use of steam