For 50 years, pharmacy students and practicing pharmacists have depended on Martin's Physical Pharmacy and Pharmaceutical Sciences to understand the application of core physical chemistry principles in the pharmaceutical sciences. By presenting topics in layers—from basic to in-depth discussions—the text enables easy comprehension of core concepts. Moreover, the text's many examples help apply these concepts to actual pharmacy practice.
This Sixth Edition has been thoroughly revised and updated, reflecting the current understanding of physical, chemical, and biological principles and their application to the pharmaceutical sciences. In addition to two new chapters, many of the chapters have been rewritten to emphasize the most important subjects taught in pharmacy education today.
Salient Features * NEW! Two new chapters offer the latest information on pharmaceutical biotechnology and solid oral dosage forms. * NEW! Completely rewritten chapters present current concepts in drug delivery and targeting, pharmaceutical polymers, and interpretive skills needed for pharmacists and pharmaceutical scientists. * Illustrative examples show how crucial physical chemistry principles are applied in pharmacy practice. * Key concept boxes highlight information essential for pharmacy practice. Chapter objectives explain what you'll know upon successful completion of the chapter.
Table of Contents 1. Interpretive Tools 2. States of Matter 3. Thermodynamics 4. Physical Properties of Molecules 5. Nonelectrolytes 6. Electrolyte Solutions 7. Ionic Equilibria 8. Buffered and Isotonic Solutions 9. Solubility and Distribution Phenomena 10. Complexation and Protein Binding 11. Diffusion 12. Biopharmaceutics 13. Drug Release and Dissolution 14. Chemical Kinetics and Stability 15. Interfacial Phenomena 16. Colloidal Dispersions 17. Coarse Dispersions 18. Micromeritics 19. Rheology 20. Pharmaceutical Polymers 21. Pharmaceutical Biotechnology 22. Oral Solid Dosage Forms 23. Drug Delivery Systems and Nanotechnology