Sedno 5mg 10's Strip Tablet

Summary:

Indications of Sedno 5 mg
Sedno 5 mg is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, nasal discharge and itching, congestion or stuffiness, as well as ocular itching, tearing and redness, itching of palate and coughing. Sedno 5 mg is also indicated for ... Read moreSedno 5 mg is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, nasal discharge and itching, congestion or stuffiness, as well as ocular itching, tearing and redness, itching of palate and coughing. Sedno 5 mg is also indicated for the relief of symptoms associated with chronic idiopathic urticaria such as the relief of itching and the size and number of hives.

Theropeutic Class
Non-sedating antihistamines

Pharmacology
Sedno 5 mg is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils.

Dosage and Administration of Sedno 5 mg
Pediatric drops : Child 6 -11 months of age: 2 ml drops once daily Child 1 -2 years of age: 2.5 ml drops once daily Syrup: Child 6-11 months of age: 2 ml once daily Child 1-5 years of age: 2.5 ml once daily Child 6-11 years of age: 5 ml once daily Adults and > 12 years of age: 10 ml once daily Tablet: Adults and children 12 years of age and over: 5 mg daily

Dosage of Sedno 5 mg
Pediatric drops: Child 6-11 months of age: 2 ml drops once daily. Child 1-2 years of age: 2.5 ml drops once daily. Syrup: Child 6-11 months of age: 2 ml once daily. Child 1-5 years of age: 2.5 ml once daily. Child 6-11 years of age: 5 ml once daily. Adults and >12 years of age: 10 ml once daily. Tablet: Adults and children 12 years of age and over: 1 tablet daily

Interaction of Sedno 5 mg
No clinically relevant drug interactions have been reported.

Contraindications
Sedno 5 mg is contraindicated in patients having hypersensitivity to this medication or to any of its ingredients or Loratadine.

Side Effects of Sedno 5 mg
Less common side effects may include headache, nausea, fatigue, dizziness, pharyngitis, dyspepsia and myalgia.

Pregnancy and Lactation
Pregnancy: There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, Sedno 5 mg should be used in pregnancy only if clearly needed. Lactation: Sedno 5 mg passes into breast milk. Therefore, a decision should be made whether to discontinue nursing or to discontinue Sedno 5 mg, taking into account the importance of the drug to the mother.

Precautions and Warnings
In adult patients with liver or renal impairment: A starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data. If the patient has medical or familial history of seizures.

Overdose Effects of Sedno 5 mg
No clinically relevant adverse effects have been reported.

Storage Conditions
Store in a cool and dry place, protected from light. Store below 30°C. Keep all medicines out of the reach of children.

Use In Special Populations
Paediatric Use: The safety and effectiveness of Sedno 5 mg in pediatric patients under 2 years of age have not been established.Geriatric Use: In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.In adult patients with liver or renal impairment: A starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data.

Drug Classes
Non-sedating antihistamines

Mode Of Action
Sedno 5 mg, the major active metabolite of Loratadine, is a non-sedating; long acting tricyclic histamine antagonist with selective H1-receptor histamine antagonist activity. Sedno 5 mg also inhibits histamine release from human mast cell.

Pregnancy
Pregnancy Category C. The safe use of Sedno 5 mg during pregnancy has not been established. Therefore, Sedno 5 mg is not to be used during pregnancy unless clearly indicated. Sedno 5 mg passes into breast milk, therefore a decision should be made whether to discontinue nursing or to discontinue Sedno 5 mg taking into account the importance of the drug to the mother.

Pediatric Uses
Recommended in the use in children and adolescents.