Dicaltrol Plus 5s' Strip Tablet image
  • Dicaltrol Plus 5s' Strip Tablet image
  • Dicaltrol Plus 5s' Strip Tablet image
  • Dicaltrol Plus 5s' Strip Tablet image
  • Dicaltrol Plus 5s' Strip Tablet image
  • Dicaltrol Plus 5s' Strip Tablet image

Dicaltrol Plus 5s' Strip Tablet

Brand: Drug International Ltd

Category: Calcitriol + Calcium Citrate

TK. 65 TK. 62 You Save TK. 3 (5%)

Product Summary & Specification

Summary:

Indications of Dicaltrol Plus

Calcitriol and Calcium combination is indicated for Osteoporosis, Hypoparathyroidism, Hypocalcaemia, Osteomalacia rickets, Renal osteodystrophy.

Theropeutic Class

Specific mineral and vitamin combined preparations

Pharmacology

Calcium salt can be used in the prevention and treatment of calcium deficiency states or negative calcium balance. It is also used as an adjunct in the prevention and treatment of osteoporosis.Calcitriol promotes calcium absorption in the intestines and retention at the kidneys thus increasing serum calcium levels. It also increases renal tubule phosphate resorption consequently decreasing serum phosphatase levels, PTH levels and bone resorption.

Dosage and Administration of Dicaltrol Plus

Hyperparathyroidism in renal failure: 0.25 mcg/day or alternate day. May increase slowly. Hypoparathyroidism or pseudohypoparathyroidism: 0.5-2 mcg once daily. Vitamin D dependent rickets: 0.015-0.02 mcg/kg/day. Maintenance: 0.03-0.06 mcg/kg/day. Max: 2 mcg/day.Hyperparathyroidism in dialysis patients: 0.5-4 mcg 3 times/wk. Max: 8 mcg 3 times/wk. Hyperparathyroidism in renal failure: 0.5 mcg 3 times/wk, may increase by 0.25-0.5 mcg at 2-4 wk intervals. Maintenance: 0.5-3 mcg 3 times/wk.

Dosage of Dicaltrol Plus

Hyperparathyroidism in renal failure: 0.25 mcg/day or alternate day. May increase slowly. Hypoparathyroidism or pseudohypoparathyroidism: 0.5-2 mcg once daily. Vitamin D dependent rickets: 0.015-0.02 mcg/kg/day. Maintenance: 0.03-0.06 mcg/kg/day. Max: 2 mcg/day.Hyperparathyroidism in dialysis patients: 0.5-4 mcg 3 times/wk. Max: 8 mcg 3 times/wk. Hyperparathyroidism in renal failure: 0.5 mcg 3 times/wk, may increase by 0.25-0.5 mcg at 2-4 wk intervals. Maintenance: 0.5-3 mcg 3 times/wk.

Interaction of Dicaltrol Plus

Calcium: Co-administration with thiazide diuretics or vit D may lead to milk-alkali syndrome and hypercalcaemia. Decreased absorption with corticosteroids. Decreases absorption of tetracyclines, atenolol, iron, quinolones, alendronate, Na fluoride, Zn and calcium-channel blockers. Enhances cardiac effects of digitalis glycosides and may precipitate digitalis intoxication.Calcitriol: Hypermagnesaemia may develop in patients on chronic renal dialysis. Hypercalcaemia in patients on digitalis may precipitate cardiac arrhythmias. Intestinal absorption of calcitriol may be reduced by cholestyramine and colestipol. Phenytoin, barbiturates may decrease the T1/2 of calcitriol. May develop hypercalcaemia with thiazide diuretics.

Contraindications

Hypercalcaemia; evidence of vitamin D toxicity, pregnancy and lactation.

Side Effects of Dicaltrol Plus

Weakness; headache; somnolence; nausea; vomiting; dry mouth; constipation; muscle pain; bone pain; metallic taste; polyuria; polydipsia; anorexia; irritability; weight loss; nocturia; mild acidosis; reversible azotemia; generalized vascular calcification; nephrocalcinosis; conjunctivitis (calcific); pancreatitis; photophobia; rhinorrhoea; pruritus; hyperthermia; decreased libido; elevated BUN; albuminuria; hypercholesterolaemia; elevated AST and ALT; ectopic calcification; hypertension; cardiac arrhythmias.

Pregnancy and Lactation

Pregnancy Category-C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Precautions and Warnings

Idiopathic hypercalcaemia. Pediatric doses must be individualised and monitored under close medical supervision. Coronary disease, renal function impairment and arteriosclerosis, especially in the elderly. Hypoparathyroidism.

Drug Classes

Specific mineral and vitamin combined preparations

Mode Of Action

Calcium salt can be used in the prevention and treatment of calcium deficiency states or negative calcium balance. It is also used as an adjunct in the prevention and treatment of osteoporosis.Calcitriol promotes calcium absorption in the intestines and retention at the kidneys thus increasing serum calcium levels. It also increases renal tubule phosphate resorption consequently decreasing serum phosphatase levels, PTH levels and bone resorption.

Pregnancy

Pregnancy Category-C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Specification:
Title: Dicaltrol Plus 5s' Strip Tablet
Brand: Drug International Ltd

Brand Information

Drug International Ltd logo
Drug International Ltd

Drug International Limited started its journey in 1974 as a private limited company, etching its journey under the Registrar of Joint Stock Companies. We are the first manufacturer of soft gel medicine leading in Bangladesh. Since its establishment, the company has maintained a strong focus on producing high-quality medicines while adhering to international standards. With an expansive portfolio covering various therapeutic areas, Drug International is committed to innovation, excellence, and contributing to the healthcare needs of the population locally and globally. From day one, our unwavering mission has been to soar beyond boundaries, aligning with global standards. Guided by the World Health Organization's Good Manufacturing Practices (WHO cGMP) guidelines, we've been scripting a legacy of excellence, one milestone at a time.Drug International Limited continues to play a crucial role in the pharmaceutical industry of Bangladesh and abroad, with a strong commitment to producing safe, effective, and innovative medicines. By combining advanced technology, a dedicated workforce, and a customer-first approach, the company is positioned as a trusted name in healthcare solutions.

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